21. Apo ( a ) contains domains that are very similar to plasminogen ( PLG ). 22. Tissue plasminogen activator ( TPA ) is a serine protease occurring in animals including humans. 23. The angiogenesis inhibitor is generated when certain enzymes cleave it out of its parent plasminogen molecule. 24. The drug, formally known as tissue plasminogen activator, does come with a worrisome catch. 25. Davidson is an expert on plasminogen . 26. -Tissue Plasminogen Activator, or TPA, a medication that fights blood clots during surgery. 27. Full length plasminogen comprises seven domains. 28. These data help explain the functional differences between the type I and type II plasminogen glycoforms. 29. Plasminogen deficiency in mice leads to defective liver repair, defective wound healing, reproductive abnormalities.30. Simultaneously, excess circulating thrombin assists in the conversion of plasminogen to plasmin, resulting in fibrinolysis.
