21. Historically, poliomyelitis was the most significant disease caused by an enterovirus, poliovirus . 22. For example, increased doses of the mutagen Ribavirin reduces the infectivity of Poliovirus . 23. The most important step in eradication of polio is interruption of transmission of poliovirus . 24. In October 1999, the last isolation of type 2 poliovirus occurred in India. 25. Researchers in this case used cysteine proteases such as papain and poliovirus 3C protease. 26. Wild Poliovirus Containment Program : www . cdc . gov / od / nvpo / polio 27. Infection with one serotype of poliovirus does not provide immunity against the other serotypes,. 28. The Sabin vaccine worked in the intestines to block the poliovirus from entering the bloodstream. 29. Two additional challenges are found in unobserved polio transmission and in vaccine-derived poliovirus . 30. This type of poliovirus was declared eradicated.
