21. These fibers intersect the Purkinje cell dendrites. 22. Purkinje cell CRs were also adaptively timed.23. Purkinje cells show spontaneous electrophysiological activity in the form of trains of spikes both sodium-dependent and calcium-dependent.24. A computational model of the Purkinje cell has shown intracellular calcium computations to be responsible for toggling. 25. Conversely, a single deep nuclear cell receives input from approximately 860 Purkinje cells ( again in cats ). 26. Purkinje cells ?! deep nuclei.27. Cartwheel cells have similar spiking patterns to Purkinje cells , firing complex spike bursts as well as simple spikes. 28. Some special cells present only in the cerebellum, Purkinje cells , have been reported to be part of this problems. 29. As the null mice age, a marked loss of Purkinje cells in the cerebellum results in decreased motor coordination. 30. But this latter study has itself been challenged and Purkinje cell toggling has since been observed in awake cats.