21. Pustules may rupture, forming erosions or become crusted.22. These inflamed papules or pustules can form especially if the area becomes infected. 23. The wound turned septic, and his entire body erupted into open pustules . 24. Unroofing the early vesicles or pustules may permit manual extraction of the spicules. 25. These comedones can become irritated, swollen and infected, leading to pustules . 26. Between seven and ten days the pustules matured and reached their maximum size. 27. The brown bark sheds irregularly; pustules and bumps give a patchy appearance. 28. The bark is fairly smooth with some raised pustules of a darker colour. 29. Pemphigus foliaceus in animals produces clusters of small vesicles that quickly evolve into pustules . 30. By the sixth or seventh day, all the skin lesions have become pustules .
