21. This enzyme participates in retinol metabolism. 22. Conversion of carotene to retinol varies from person to person and bioavailability of carotene in food varies. 23. Retinol then attaches to a serum carrier, retinol binding protein, for transport to target tissues.24. Retinol then attaches to a serum carrier, retinol binding protein, for transport to target tissues. 25. The conversion of retinol to retinal is the rate-limiting step in the retinoic acid biosynthesis. 26. Some makers of multivitamins and vitamin A supplements have begun replacing some retinol with beta carotene, she said. 27. Retinol enters the absorptive cells of the small intestine, preferentially in the all-trans-retinol form.28. Retinol enters the absorptive cells of the small intestine, preferentially in the all-trans-retinol form. 29. It is possible that a retinol ( vitamin A ) deficiency alone could cause albumin levels to become raised. 30. Retinol and retinoic acid play crucial roles in the modulation of gene expression and overall development of an embryo.