In 1991 it became part of the University of Milan, and today primarily cultivates plants of interest for medicine and pharmaceutics, but also supports research in transgenic plants, rice, etc . Collections include " Camptotheca acuminata ", " Eschscholzia ", " Nicotiana ", " Nigella ", " Scutellaria ", and " Solanaceae ".
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A variety of flavonoids in " Scutellaria " species have been found to bind to the benzodiazepine site and / or a non-benzodiazepine site of the GABA A receptor, including baicalin, baicalein, wogonin, apigenin, oroxylin A, scutellarein, and skullcapflavone II . Baicalin and baicalein, wogonin, and apigenin have been confirmed to act as positive allosteric modulators and produce anxiolytic effects in animals, whereas oroxylin A acts as a negative allosteric modulator ( and also, notably, as a dopamine reuptake inhibitor ).
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