21. During Squibb s effort to synthesis secretin , Ondetti stopped carrying a lab notebook. 22. Gastrin and secretin may also act as secretagogues. 23. These and other testimonials sparked a huge demand for off-label secretin use. 24. However, they relied on a single dose of secretin with four weeks of observation. 25. Secretin is a hormone made in the intestine that stimulates the release of digestive fluids.26. And, like Mary O'Neal, they pray that secretin is that nudge. 27. Secretin is a digestive enzyme best known as a controversial, unproven treatment for autism.28. Secretin targets the pancreas; pancreatic centroacinar cells have secretin receptors in their plasma membrane.29. Secretin targets the pancreas; pancreatic centroacinar cells have secretin receptors in their plasma membrane. 30. Bayliss and Ernest Henry Starling discovered the peptide hormone secretin and peristalsis of the intestines.