21. Splicing optical fibres is much more difficult than connecting copper wires.22. Abelson was a key figure in the elucidation of RNA splicing . 23. Alternatively spliced transcript variants encoding the same protein have been observed. 24. Several genetic diseases may be the result of splice site mutations. 25. Alternative splicing results in multiple transcript variants encoding distinct isoforms ." 26. This mutation is in a splice acceptor site of exon 3. 27. He has developed an art form that splices drama with magic. 28. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. 29. Two alternatively spliced transcript variants encoding distinct isoforms have been reported. 30. Alternatively spliced transcript variants encoding the distinct isoforms have been described.