21. Telomeres prevent them from breaking and getting tangled up with one another.22. Evidence can be found for recombination between several different groups of telomeres . 23. Many aging-related diseases are linked to shortened telomeres . 24. Blackburn co-discovered telomerase, the enzyme that replenishes the telomere . 25. In humans and other animals, telomeres almost always shorten with age. 26. RIF1 and RIF2 cap the chromosome ends ( telomeres ) in yeast. 27. The currently accepted terminology for these sequences is " mega-telomeres " 28. DUF domains are involved in telomere maintenance and meiotic segregation. 29. TERRA can also regulate telomere length by increasing euchromatin formation. 30. Telomerase is like a tiny molecular carpenter that rebuilds telomeres as they shorten.