Sparteine is a lupin alkaloid containing a tetracyclic bis-quinolizidine ring system derived from three C 5 chains of lysine, or more specifically, L-lysine.
22.
TCAs, or tetracyclic-heterocyclics, were safer, but they also had side effects from dry mouth to drowsiness _ and in case of overdoses, cardiac problems.
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It was synthesized under the hypothesis that a polyanionic cyclization ( double Michael addition followed by aldol condensation ) would allow access to a tetracyclic intermediate with the desired functionality.
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It was concluded that biological activity is dependent upon an optimal conformation defined by a narrowly fixed angle between the planes of the C6-indole and the tetracyclic unit.
25.
"' Dammarane "'is a tetracyclic triterpene found in sapogenins ( forming triterpenoid saponins ) like those of ginseng ( ginsenosides : panaxatriol and protopanaxadiol ).
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The Weinreb group ( 2014 ) used a conjugative addition of an indole precursor to an oxime-substituted nitrosoalkene to generate the tetracyclic skeleton of conolidine in 4 steps.
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However, Risperidone tends to have a higher incidence of extrapyramidal effects when compared to the tricyclic and tetracyclic atypical antipsychotics, such as quetiapine, clozapine, olanzapine, etc.
28.
It is a dammarane-type tetracyclic triterpene sapogenin found in ginseng ( " Panax ginseng " ) and in notoginseng ( " Panax pseudoginseng " ).
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It is a dammarane-type tetracyclic terpene sapogenin found in ginseng ( " Panax ginseng " ) and in notoginseng ( " Panax pseudoginseng " ).
30.
It is a dammarane-type tetracyclic triterpene sapogenins found in ginseng ( " Panax ginseng " ) and in notoginseng ( " Panax pseudoginseng " ).
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