21. It contains a substance ( theobromine ) that can be toxic to dogs and cats. 22. The dose of theobromine was equal to that found in seven ounces of dark chocolate. 23. Theophylline is very closely related to caffeine and theobromine , mild central nervous system stimulants. 24. :Our article on theobromine poisoning says that parrots are very susceptible to chocolate poisoning. 25. The lethal dose for dogs is approximately 100 milligrams of theobromine per kilogram of body weight. 26. Theobromine is also toxic to some animals unable to metabolize it ( see theobromine poisoning ).27. Theobromine is also toxic to some animals unable to metabolize it ( see theobromine poisoning ). 28. Although not usual, the effects of theobromine poisoning, as stated, can become fatal. 29. The excreted metabolites are mostly paraxanthines theobromine and theophylline and a small amount of unchanged caffeine. 30. Chocolate contains alkaloids such as theobromine and phenethylamine, which have physiological effects on the body.