A study conducted by measuring the intraoral vapour levels over a 24-hour period in patients with at least nine amalgam restorations showed that the average daily dose of inhaled mercury vapour was 1.7 ?g ( range from 0.4 to 4.4 ?g ), which is approximately 1 % of the threshold limit value of 300 to 500 ?g / day established by the WHO, based on a maximum allowable environmental level of 50 ?g / day in the workplace.
22.
The current ACGIH threshold limit value ( TLV ) for worker exposure is 20 ppm in the industrial atmosphere, which is well above the odor threshold of 0.4 ppm . 2-butoxyethanol is metabolized in animals by the enzyme alcohol dehydrogenase . [ 8 ] Blood or urine concentrations of 2-butoxyethanol or its major toxic metabolite, 2-butoxyacetic acid, may be measured using chromatographic techniques to monitor worker exposure or to confirm a diagnosis of poisoning in hospitalized patients.
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The findings in rats at the concentration of 4 to 10 ppm are shown in pictures . " In light of the finding of liver damage in rats from just 4 10 ppm of vinyl chloride exposure, Viola added that he " should like some precautions to be taken in the manufacturing plants polymerizing vinyl chloride, such as a reduction of the threshold limit value of monomer & " In 1970, Viola, reported that test animals exposed to 30, 000 ppm of vinyl chloride developed cancerous tumors.
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