On the other hand, ALOX5 gene knockout mice demonstrate an enhanced resistance and lessened pathology to Brucella abortus infection and, at least in its acute phase, Trypanosoma cruzi infection.
22.
They were detected in vicinity of the contractile vacuole in " Trypanosoma cruzi " and were shown to fuse with the vacuole when the cells were exposed to osmotic stress.
23.
They were detected in the vicinity of the vacuole in " Trypanosoma cruzi " and were shown to fuse with the vacuole when the cells were exposed to osmotic stress.
24.
Since mammalian CBS contains a heme cofactor, whereas yeast and protozoan enzyme from Trypanosoma cruzi do not have heme cofactors, researchers have speculated that heme is not required for CBS activity.
25.
"Trypanosoma cruzi " is a member of the same genus as the infectious agent of African sleeping sickness, but its clinical manifestations, geographical distribution, life cycle and insect vectors are quite different.
26.
Trypanosomes infect a variety of hosts and cause various diseases, including the fatal human diseases sleeping sickness, caused by " Trypanosoma brucei ", and Chagas disease, caused by " Trypanosoma cruzi ".
27.
The most notable is American trypanosomiasis, known as Chagas disease, which occurs in South America, caused by " Trypanosoma cruzi ", and transmitted by certain insects of the Reduviidae, members of the Hemiptera.
28.
In Brazil, sugarcane juice has been linked to cases of Chagas disease, as sugarcane can contain traces of its responsible pathogen, " Trypanosoma cruzi ", left by infected bugs if not properly cleaned.
29.
Chagas also persuaded Argentine physician Salvador Mazza to research the epidemic, leading to the latter's confirmation of the existence of " trypanosoma cruzi " in Argentina in 1927, and eventually to government action.
30.
For example, in the figure showing trypanothione reductase from the human protozoan parasite " Trypanosoma cruzi ", two molecules of an inhibitor called " quinacrine mustard " are bound in its active site.
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