Albinism results in a lack of melanin ( due to a defect in the tyrosinase mediated melanogenesis pathway ).
22.
This precludes the bidentate coordination complex necessary for di-phenolate hydroxylation characteristic of tyrosinase but absent in catechol oxidase.
23.
Xenbase was utilized to obtain publicly available sequences for tyrosinase ( tyr ) and pax6, needed for TALEN design.
24.
This is due to a reduction in the enzyme tyrosinase which indirectly controls the production of melanin, a dark colouring.
25.
There is one canine tumor vaccine approved by the T-cell responses and antibodies against tumor-specific tyrosinase proteins.
26.
A critical step in the production of melanins is the catalysis of tyrosine by an enzyme called tyrosinase, producing dopaquinone.
27.
For instance, scaffolded histidine residues mimics certain metalloproteins and-enzymes such as hemocyanin, tyrosinase, and catechol oxidase ).
28.
In addition to its role in melanin synthesis, Tyrp1 is involved in stabilizing of tyrosinase protein and modulating its catalytic activity.
29.
Hemocyanin is homologous to the phenol oxidases ( e . g . tyrosinase ) since both enzymes sharing type copper active site coordination.
30.
Her dissertation " Mechanisms of Pigment Formation " examined the way melanin pigment granules could be formed in vitro using the enzyme tyrosinase.
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