21. Infections are associated with mucosal ulceration , rectal bleeding, and drastic dehydration. 22. Areas of prior ulceration may leave behind permanent scarring. 23. The Japanese Chin's flattened ulcerations can result. 24. Sometimes aphthous-like ulcerations can be the only sign of celiac disease. 25. Special investigations may be indicated to rule out other causes of oral ulceration . 26. Early lesions have a central zone of ulceration covered by a fibrinous membrane. 27. This is followed by considerable swelling, blistering, necrosis, and ulceration . 28. Symptoms in children include extreme freckling, multiple skin cancers and corneal ulcerations . 29. Recurrent ulceration and fat necrosis is associated with lipodermatosclerosis. 30. It can be described as a sublingual traumatic ulceration .