21. Second-hand smoke is also associated with impaired vasodilation among adult nonsmokers. 22. The body s tissues have the ability to sense hypoxia and induce vasodilation . 23. Overall, this leads to relaxation of the smooth muscle and coronary vasodilation . 24. Most notably, this enzyme is involved in vasodilation . 25. Axon reflex regulates vasodilation , or the extra blood flow to target tissues. 26. It is associated with the decrease in myocardial stress due to peripheral vasodilation . 27. Increased endothelin and decreased vasodilation has been documented. 28. Endothelin and prostanoids cause vasoconstriction in placental arteries, while nitric oxide causes vasodilation . 29. Several proposed pathways of NO-induced vasodilation have been proposed through haemodynamic investigation. 30. They inhibit phosphodiesterase and thus increasing cAMP, exerting positive inotropy and causing vasodilation .