The anterior part of the saccule exhibits an oval thickening, the "'macula acustica sacculi "', or macula, to which are distributed the saccular filaments of the vestibular branch of the vestibulocochlear nerve, also known as the statoacoustic nerve or cranial nerve VIII.
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The most common vestibular diseases in humans are Vestibular neuritis, a related condition called Labyrinthitis, M�ni�re's disease, and BPPV . In addition, the function of the vestibular system can be affected by tumors on the vestibulocochlear nerve, an infarct in the brain stem or in cortical regions related to the processing of vestibular signals, and cerebellar atrophy.
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