A genital skin fibroblast study and a human chorionic gonadotropin ( hCG ) stimulation test may also provide information helpful in the assessment of virilization capacity.
22.
Another common disorder is congenital adrenal hyperplasia where the adrenal glands produce excessive sex hormones during development leading to virilization of a 46, XX female.
23.
Cases of virilization caused by topical exposure to testosterone are rare in the medical literature, said Dr . Y . Miles Yu, the lead author of the study.
24.
Often present are increased muscle mass, clitoral enlargement may occur in girls, and sometimes a degree of prenatal virilization is recognized that may have gone unnoticed in infancy.
25.
The most common instance of this is when a child will be assigned and raised as a female despite complete virilization, as with Prader 5 reassigned as a female.
26.
Case reports of significant virilization of young children after exposure to topical androgen preparations ( both prescription and'supplement'products ) used by their caregivers demonstrates this very real risk.
27.
With greater degrees of virilization, the major challenge of the procedure is to provide a passage connecting the outer vaginal opening to the cervix which will stay wide enough to allow coitus.
28.
Theoretically, if enough glucocorticoid could be supplied to the fetus to reduce adrenal testosterone production by the 9th week, virilization could be prevented and the difficult decision about timing of surgery avoided.
29.
The excess of adipose tissue in obese women creates the paradox of having both excess androgens ( which are responsible for hirsutism and virilization ) and estrogens ( which inhibits FSH via negative feedback ).
30.
Milder forms resulting from incomplete loss of 3?-HSD type II function do not present with adrenal crisis, but can still produce virilization of genetically female infants and undervirilization of genetically male infants.
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