21. CCCVd have a sequence of 246 nucleotides, 44 of which are common with most viroids . 22. The viroid can also be detected by a more sensitive method called Dot blot molecular hybridization. 23. The human pathogen hepatitis D virus is a " defective " RNA virus similar to a viroid . 24. Prior to death, the viroid causes its host's powers to flare out of control. 25. File : Viroids -how it do . gif | The reproduction mechanism of a typical viroid. 26. File : Viroids-how it do . gif | The reproduction mechanism of a typical viroid . 27. Some microbiologists also classify viruses ( and viroids ) as microorganisms, but others consider these as nonliving. 28. Therefore, they are similar to viroids in terms of their means of replication ( Rolling circle replication ). 29. ASBV is the smallest known viroid that infects plants and is transmitted by pollen and infected seeds or budwood. 30. Viroids levels can vary by 1000 times between branches on the same tree and by 10000 times between trees.