Companies began developing the new acellular vaccines after several countries halted the use of the whole cell vaccines due to side effects.
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Tdap is given as a onetime, first time only dose that includes the tetanus, diphtheria, and acellular pertussis vaccinations.
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This month, the American Academy of Pediatrics is releasing a special 12-study report on a new vaccine, acellular pertussis.
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New acellular pertussis vaccines were developed in the 1980s, which included only a few selected pertussis antigens ( toxins and adhesins ).
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According to a lead author of the report, results are so promising that acellular pertussis could go into wide use within a year.
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_Acellular vaccine can safely be combined with HiB vaccine ( against fatal meningitis ) without generating side effects or damping the immune response.
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Also on the horizon is Chiron Corp . which submitted an application to the FDA for its own acellular pertussis vaccine in late September.
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The so-called acellular pertussis vaccines use only a piece of killed pertussis bacteria instead of the whole cell used in older vaccines.
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North American Vaccine Inc . and Chiron Corp . are also developing acellular pertussis vaccines, though they have yet to win FDA approval.
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While the old vaccine was based on whole cells, the new one is acellular, made from only part of the infectious organism.
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