31. It can also act on aldosterone , corticosterone and cortisol, to some extent. 32. Aldosterone plays a central role in regulating blood pressure through its effects on the kidney.33. The primary mineralocorticoid is aldosterone , notable for an aldehyde group at the 18 position. 34. This leads to increased Ca 2 + influx, which in turn triggers aldosterone production. 35. This results in less StAR protein product and decreased levels of aldosterone and cortisol synthesis. 36. The pathophysiological consequences of PHA are a result of abnormal increases in the hormone aldosterone . 37. Aldosterone receptors are present on the epithelial cells of the distal nephron in the kidney.38. It is the inhibitor of aldosterone biosynthesis. 39. When CYP11B1 and CYP11B2 are abnormally fused together, too much aldosterone synthase is produced. 40. Aldosterone , probably acting through mineralocorticoid receptors, may positively influence neurogenesis in the dentate gyrus.
