31. If afflicted with severe anaemia , an expectant mother may become very tired and weak. 32. Mildly affected patients experience a compensated haemolytic anaemia because mutations affect stability of the enzyme. 33. He is a recognised authority on anaemia , sickle cell disease and malaria in pregnancy. 34. A highly relevant observation is that different mutations produce Fanconi anaemia phenotypes of varying severity. 35. In 1887 he suffered at attack of pernicious anaemia , leaving him in poor health. 36. One in four suffers from anaemia . 37. In humans, it has been demonstrated to be successful in treating anaemia and hereditary angioedema. 38. Nicosan did not appear to affect the risk of severe complications or the level of anaemia . 39. Symptoms, such as severe anaemia and heart attack, appear within two years after birth. 40. Clinical signs may also include anaemia .
