Different species normally have different numbers of chromosomes from one another, and the terms " aneuploid " and " polyploid " refer to the chromosome number being different from the usual number for that species.
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As with several other endocrine tumors, malignancy cannot be determined from the histologic appearance; tumors that contain large number of aneuploid or tetraploid cells, as determined by flow cytometry, are more likely to recur.
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A meta-analysis of more than 800 embryos came to the result that approximately 75 % of preimplantation embryos are mosaic, of which approximately 60 % are diploid aneuploid mosaic and approximately 15 % aneuploid mosaic.
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A meta-analysis of more than 800 embryos came to the result that approximately 75 % of preimplantation embryos are mosaic, of which approximately 60 % are diploid aneuploid mosaic and approximately 15 % aneuploid mosaic.
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Organisms in which a particular chromosome, or chromosome segment, is under-or overrepresented are said to be aneuploid ( from the Greek words meaning " not ", " good ", and " fold " ).
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The existence of supernumerary or B chromosomes means that chromosome number can vary even within one interbreeding population; and aneuploids are another example, though in this case they would not be regarded as normal members of the population.
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Her research group recently created haploid yeast cells containing extra copies of chromosomes and discovered that these aneuploid strains elicit phenotypes independent of the identity of the additional chromosome such as defects in cell cycle progression, increased energy demands, and interference with protein biosynthesis.
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The principle behind it is that, since it is known that numerical chromosomal abnormalities explain most of the cases of pregnancy loss, and a large proportion of the human embryos are aneuploid, the selective replacement of euploid embryos should increase the chances of a successful IVF treatment.
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