Kisspeptin-expressing neurons reside in the anteroventral periventricular nucleus and the arcuate nucleus, among others, and send projections into the MPOA, where there is an abundance of GnRH cell bodies.
32.
If the childhood inhibition of the arcuate nucleus is interrupted prematurely by injury to the brain, it may resume pulsatile gonadotropin release and puberty will begin at an early age.
33.
Further studies with db / db mice with lesions in the arcuate nucleus of the hypothalamus suggested that the receptor for the satiety factor was found in these brain receptors.
34.
The arcuate nucleus is affected and controlled by neuronal input from other areas of the brain and hormonal input from the gonads, adipose tissue and a variety of other systems.
35.
As the substance builds up in the circulation, it crosses the blood-brain barrier and activates " inhibitory " neurons in a part of the brain's hypothalamus called the arcuate nucleus.
36.
Secretin and its receptor are found in discrete nuclei of the hypothalamus, including the paraventricular nucleus and the arcuate nucleus, which are the primary brain sites for regulating body energy homeostasis.
37.
These are not the only peptides in the arcuate nucleus; ?-endorphin, dynorphin, enkephalin, galanin, ghrelin, growth-hormone releasing hormone, neurotensin, neuromedin U, and somatostatin are also expressed in subpopulations of arcuate neurons.
38.
The "'arcuate nucleus "'of the hypothalamus ( also known as ARH, ARC, or infundibular nucleus ) is an aggregation of neurons in the mediobasal hypothalamus, adjacent to the third ventricle and the median eminence.
39.
The circuit begins with an area of the hypothalamus, the arcuate nucleus, that has outputs to the lateral hypothalamus ( LH ) and ventromedial hypothalamus ( VMH ), the brain's feeding and satiety centers, respectively.
40.
Dynorphin acts through ?-opioid receptors, and is widely distributed in the CNS, including in the spinal cord and hypothalamus, including in particular the arcuate nucleus and in both oxytocin and vasopressin neurons in the supraoptic nucleus.
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