31. Finally, the acyl azide reacts in the normal manner to give the urethane. 32. If you plan on actually making sodium azide , please be careful with it. 33. The free hydroxyl of this was subsequently substituted by an azide to give 32. 34. It was first obtained by Theodor Curtius in 1890, along with other azides . 35. Azides are cleanly reduced to amines in preference to sterically hindered aliphatic nitro groups:36. The monomers used in this polymerization are oligopeptides with terminal azide and terminal alkyne groups 37. This 2-hydroxy structure is then reacted with azide and a nucleophilic base. 38. Sodium azide is a hazardous substance, highly explosive and tricky to handle in manufacturing. 39. Sodium azide is a notoriously dangerous chemical. 40. Sodium azide increases cyclic GMP levels in brain and liver by activation of guanylate cyclase.
