Traditionally, chemotherapeutic adjuvants, such as mitomycin C ( MMC ) or 5-fluorouracil ( 5-FU ), are applied with soaked sponges on the wound bed to prevent filtering blebs from scarring by inhibiting fibroblast proliferation.
32.
In addition, the free-floating blebs themselves may cause a useless stimulation of the immune system, resulting in the production of antibodies that mistakenly attack the body's own tissues and the release of brain-damaging toxins.
33.
One of the proteins activated by the presence of calcium in the cell is calpain, a Ca 2 +-dependent non-blebs and the breakdown of the cytoskeleton and the membrane, and ultimately the death of the cell.
34.
Bleb growth is driven by intracellular pressure generated in the cytoplasm when the actin cortex undergoes actomyosin contractions, leading to the eventual break up into several billion pieces because the pressure is different than the exterior surface of the growth anatomical presence.
35.
When the electrode is pulled far enough away, this bleb will detach from the cell and reform as a convex membrane on the end of the electrode ( like a ball open at the electrode tip ), with the original outside of the membrane facing outward from the electrode.
36.
In comparison to the glaucoma drainage devices that use an ab externo procedure, ab interno implants, such as the Xen Gel Stent, are transscleral implants to channel aqueous humor into the non-dissected Tenon's space, creating a subconjunctival drainage area similar to a bleb.
37.
Bleb forming procedures include ab externo trabeculectomy and deep sclerectomy . in order to prevent wound adhesion after deep scleral excision and maintain good filtering results, it is sometimes performed with a variety of biocompatible spacer or device, such as the Aquaflow collagen wick, ologen Collagen Matrix, or Xenoplast glaucoma implant.
38.
Ice, did I say I was like shattered ice ? _ a mud pool, more like, hot and heaving, and the thought of her a bubble rising and steadily swelling and then breaking the surface and bursting with an awful plop while down in the depths another bleb of turbid speculation was already forming itself.
39.
Serum amyloid P component is a protein that is thought to aid in the clearance of chromatin produced by apoptotic cells and deficiencies in this protein have been shown ( in mice ) to cause spontaneous formation of ANA . Autoantigens present on the blebs of apoptotic cells are also prone to modification, which can increase their immunogenicity.
40.
As the skin lesions are typically painful, it is also often necessary to exclude other painful tumors of the skin ( including blue rubber bleb nevus, leiomyoma, eccrine spiradenoma, neuroma, dermatofibroma, angiolipoma, neurilemmoma, endometrioma, glomus tumor and granular cell tumor; the mnemonic " BLEND-AN-EGG " may be helpful ).
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