31. This causes bradycardia and peripheral vasoconstriction. 32. However the greatest bradycardia effect is induced when the subject is holding breath with face submerged. 33. Hypertension followed by hypotension, bradycardia , and respiratory depression lower tissue oxygenation in the skin. 34. This is referred to as sinoatrial block typically manifesting with various degrees and patterns of sinus bradycardia 35. A permanent pacemaker may be placed in situations where the bradycardia is not expected to recover. 36. In addition, bradycardia , itching, nausea, vomiting and some abdominal pain have been recorded. 37. This induces bradycardia , or slowed heart rate, and signifies the second stage of the reflex. 38. Bradycardia may also be caused by increased ICP due to direct mechanical distortion of the vagus nerve.39. Mechanical distortion of the vagus nerve stimulates a parasympathetic response, which can in turn induce bradycardia . 40. However, prolonged disinhibition can be lethal for mammals, as it results in apnea and bradycardia .
