Although this problem appears quite complex, it can be accurately solved with a branch and bound search tree algorithm or tightly upper bounded with a single multiplication of a matrix with a vector.
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There has also been extensive research on heuristic algorithms for solving maximum clique problems without worst-case runtime guarantees, based on methods including branch and bound, local search, greedy algorithms, and constraint programming.
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Branch and bound algorithms use this representation to efficiently explore the conformation tree : At each " branching ", branch and bound algorithms " bound " the conformation space and explore only the promising branches.
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Branch and bound algorithms use this representation to efficiently explore the conformation tree : At each " branching ", branch and bound algorithms " bound " the conformation space and explore only the promising branches.
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Another method involves the use of branch and bound techniques, where the program is divided into subclasses to be solved with convex ( minimization problem ) or linear approximations that form a lower bound on the overall cost within the subdivision.
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"' PM2 "'is an open-source distributed multithreaded programming environment designed to support efficiently distributed programs with a highly irregular behavior ( e . g . branch and bound search, computation on sparse matrices, etc . ) on distributed architectures.
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Further, when solving the LP relaxations, additional cutting planes may be generated, which may be either " global cuts ", i . e ., valid for all feasible integer solutions, or " local cuts ", meaning that they are satisfied by all solutions fulfilling the side constraints from the currently considered branch and bound subtree.
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