31. Its C-terminal region lacks any homology to the calmodulin -like domain of other calpains. 32. Similar to Protein Kinase C, calmodulin is activated by calcium, further promoting the cortical reaction. 33. Calmodulin participates in an intracellular signaling system by acting as a diffusible second messenger to the initial stimuli.34. This results in a host of cellular responses through stimulation of calcium-sensitive proteins such as Calmodulin . 35. The EF-hand consists of two signaling protein calmodulin and in the muscle protein troponin-C. 36. Thus, the two products are S-adenosylhomocysteine and calmodulin N6-methyl-L-lysine. 37. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin . 38. Members of this family play a role in cytoskeletal regulation, protein kinase C signaling and calmodulin signaling. 39. This gene encodes a protein with high similarity to the calcium-binding proteins of the calmodulin family. 40. Calcium / calmodulin -dependent phosphorylation of synapsin I causes dissociation of synapsin I from the vesicular membrane.