The excessive daytime sleepiness and cataplexy often become severe enough to cause serious problems in a person's social, personal, and professional life.
32.
The 3rd edition of the ICSD labels narcolepsy caused by hypocretin deficiency as " type 1 narcolepsy, " which is almost always associated with cataplexy.
33.
In most patients, it also results in cataplexy, episodes of paralysis or weakness caused by strong emotion, such as laughter, anger, or surprise.
34.
They feel exhausted most of the time, and many also experience cataplexy, brief episodes of loss of muscle control that may occur for no apparent reason.
35.
Cataplexy often strikes people with narcolepsy _ an estimated 125, 000 in the United States _ in which the sufferer has great difficulty remaining awake during the day.
36.
For example, the lack of muscular control can occur during wakefulness in a cataplexy episode; it is said that there is intrusion of REM atonia during wakefulness.
37.
Van Dijk and his colleagues were exploring a debilitating medical condition known as cataplexy, in which people collapse and sometimes injure themselves in moments of emotion, especially laughter.
38.
Along with the sleep attacks, some narcoleptics can suffer from cataplexy, sudden episodes where they lose muscle function and experience a weakness in the knees or total body collapse.
39.
Stimulants help keep him awake, to prevent cataplexy he takes Xyrem, an experimental medicine containing the compound GHB, which has been infamous as a date-rape drug.
40.
However, anywhere from 20, 000 to 50, 000 narcolepsy patients also suffer from cataplexy, a muscle-weakness complication that can cause people to collapse without warning.
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