31. Paracentric inversions do not include the centromere and both breaks occur in one arm of the chromosome. 32. It specifically stains constitutive heterochromatin, which are regions of the chromosome at or near the centromere . 33. However, in Roberts syndrome cell division, the copies are frequently not attached at the centromere . 34. DNA sequences are both necessary and sufficient to specify centromere identity and function in organisms with point centromeres. 35. DNA sequences are both necessary and sufficient to specify centromere identity and function in organisms with point centromeres . 36. For example, histone H3-like CenpA is associated with only the centromere region of the chromosome. 37. Minisatellites are prominent in the centromeres and telomeres of chromosomes, the latter protecting the chromosomes from damage. 38. The centromere is required for binding spindle fibres to separate sister chromatids into daughter cells during cell division. 39. Phosphorylation of CENP-A at serine 7 by Aurora A kinase recruits Aurora B to the centromere . 40. Aurora B has been shown to recruit MCAK to the centromere and directly phosphorylate MCAK on various residues.
