Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma.
32.
In 1971, DES was shown to cause clear cell carcinoma, a rare vaginal tumor in girls and women who had been exposed to this drug " in utero ".
33.
Signet ring and clear cell adenocarcinoma are no longer histological subtypes, but rather cytological features that can occur in tumour cells of multiple histological subtypes, most often solid adenocarcinoma.
34.
Despite the similarities in names, " clear cell sarcoma of the kidney " is unrelated to clear cell sarcoma of soft tissue, also known as malignant melanoma of soft parts.
35.
On their third try, they drew Casey, an honor roll student and tennis buff who has been battling a rare form of cancer of the connective tissues, clear cell sarcoma.
36.
Despite the similarities in names, " clear cell sarcoma of the kidney " is unrelated to clear cell sarcoma of soft tissue, also known as malignant melanoma of soft parts.
37.
ARID1A, which often carries a point mutation in Type I endometrial cancer, is also mutated in 26 % of clear cell carcinomas of the endometrium, and 18 % of serous carcinomas.
38.
The incidence of the vaginal cancers, known as clear cell adenocarcinomas, peaked after a few years, although the condition continues to occur among so-called " DES daughters " at higher-than-normal rates.
39.
Over time, sporadic mutation in the second copy of the VHL protein can lead to carcinomas, in particular hemangioblastomas affecting the liver and kidneys, renal ( and vaginal ) clear cell adenocarcinomas.
40.
SPOP is another tumor suppressor gene found to be mutated in some cases of endometrial cancer : 9 % of clear cell endometrial carcinomas and 8 % of serous endometrial carcinomas have mutations in this gene.
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