31. In 1812, Biot turned his attention to the study of optics, particularly the corpuscles . 32. Vater-Pacini corpuscles are present. 33. The urinary pole is where the corpuscle opens into the lumen of the proximal convoluted tubule. 34. There are four main types of mechanoreceptors in the glabrous skin of humans : Ruffini corpuscles . 35. Pacinian corpuscles sense changes in pressure and vibration to monitor the rate of acceleration of movement. 36. Thompson did experiments that showed it was a flow of tiny corpuscles , as he called them. 37. Others rushed to help plug a sudden hole in the dike like white corpuscles attacking an intruder. 38. That ends a 50-year arrangement with the American Red Cross, where my corpuscles go. 39. The batch of blood containing the corpuscles had been tested for the AIDS virus and found negative. 40. There are two poles in the renal corpuscle , a vascular pole, and a urinary pole.