31. The mechanism for cytotoxicity has not been extensively studied, but there has been possible mechanisms proposed. 32. The coupled bioluminescent method aCella TOX is now in widespread use for ADCC and other cytotoxicity assessments. 33. This choice was made as TGN1112 showed antibody-dependent cellular cytotoxicity on CD28 + Jurkat cells. 34. It also is responsible for some antitumor affects through antibody-dependent cellular cytotoxicity ( ADCC ). 35. Natural killer ( NK ) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation. 36. However, both direct viral cytotoxicity and secondary host immune responses may lead to the eventual pathogenesis. 37. However, in other cell lines, the MTT assay and several other assays revealed some cytotoxicity . 38. Natural cytotoxicity receptors directly induce apoptosis after binding to Fas ligand that directly indicate infection of a cell. 39. Both the plant and the extract harmine exhibit cytotoxicity with regards to HL60 and K562 leukemia cell lines. 40. Like other platinum compounds, its cytotoxicity is thought to result from inhibition of DNA synthesis in cells.
