31. It is a non-competitive reversible inhibitor of monoamine oxidase A that exhibits selective action on serotonin deamination . 32. Deamination of purine bases can result in accumulation of such nucleotides as ITP, dITP, XTP, and dXTP.33. Bernheim also detected that the enzyme facilitated the occurrence of deamination in tyramine, along with the process of oxidation. 34. In the human body, deamination takes place primarily in the liver, however glutamate is also deaminated in the kidneys. 35. It showed that when an " exo " methylamine underwent Demjanov nitrous acid deamination , ring enlargement was not produced. 36. APOBEC3G belongs to the family of cytidine deaminases that catalyze the deamination of cytidine to uridine in the single stranded DNA substrate. 37. PLP is a versatile catalyst, acting as a coenzyme in a multitude of reactions, including decarboxylation, deamination and transamination. 38. Several of these keto acids are intermediates in the citric acid cycle, for example the deamination of glutamate forms ?-ketoglutarate. 39. The deamination ( and resulting oxidation ) at position 4 yields a carbonyl group and results in a change from cytidine to uridine. 40. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine.
