31. This molecule closes potassium ion channels, leading to depolarization and neurotransmitter release. 32. Depolarization often occurs via the influx of sodium ions to the intracellular region.33. The rapid depolarization period typically lasts 3 5 ms. 34. NMDARs are known to be coincidence detectors of presynaptic activity and postsynaptic depolarization . 35. High potassium concentrations in the plasma cause depolarization of the zona glomerulosa cells membranes. 36. When acetylcholine binds to an already depolarized receptor, it cannot cause further depolarization . 37. This outward potassium current causes a small dip in membrane potential shortly after depolarization . 38. NMDA receptor ( NMDAR )-mediated currents are directly related to membrane depolarization . 39. During depolarization , the charge within the cell rapidly shifts from negative to positive. 40. These neurotransmitters bind to receptors on the postsynaptic membrane and lead to its depolarization .
