In American samples, males significantly outscored females in total sensation seeking, thrill and adventure seeking, boredom susceptibility, and disinhibition.
32.
The disinhibition of the thalamus leads to activation of the prefrontal cortex and ventral striatum, selective for increased D1 activity leading to reward.
33.
However, in societies in which the people do not expect that alcohol will disinhibit, intoxication seldom leads to disinhibition and bad behavior.
34.
Removal of such input constitutes disinhibition, which, if other sources of excitation are present in the inhibitory input, can augment excitation.
35.
Cytowic and Eagleman find support for the disinhibition idea in the so-called acquired forms head trauma, stroke, and brain tumors.
36.
They immediately note Nick has frontal lobe disinhibition, which causes him to speak his mind and have no control over what he says.
37.
Presumably, leptin fits into this act of disinhibition, but where and how the protein works its black magic have yet to be determined.
38.
The direct pathway, originating in the dorsal striatum inhibits the GPe and SNr, resulting in a net disinhibition or excitation of the thalamus.
39.
Increased dopamine results in inhibition of the Ventral pallidum, entopeduncular nucleus, and substantia nigra pars reticulata, resulting in disinhibition of the thalamus.
40.
Williams syndrome is also strongly associated with attention deficit hyperactivity disorder and related psychological symptoms such as poor concentration, hyperactivity, and social disinhibition.
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