The strands of a helical DNA duplex, if covalently closed into a circular structure, are circular DNA replication, these twists must be removed for the daughter strands to separate.
32.
Gene conversion may also occur during recombinational repair involving a DHJ, and this gene conversion may be associated with physical recombination of the DNA duplexes on the two sides of the DHJ.
33.
Using nucleic acid segments that bind to the DNA duplexes to form triple strands as a way of regulating gene expression is under investigation by biotechnology companies and ( separately ) Yale University.
34.
The coding end is highly distorted with one base flipped out from the DNA duplex in the active center, which facilitates the hairpin formation by a potential two-metal ion catalytic mechanism.
35.
The presence of cisplatin would bend the DNA duplexes by 95o and thus the toxicity to DNA, although it is not sufficiently toxic to all cancers such as breast, prostate and colon.
36.
Following Meselson-Stahl, the process of DNA replication is semi-conservative, whereby during replication the original DNA duplex is separated into two daughter strands ( referred to as the leading and lagging strand templates ).
37.
G-C base-pairs have more hydrogen bonds holding them together ( 3 ) than A-T base-pairs ( with 2 ), but that only really affects the stability of the DNA duplex.
38.
It is shorter and wider than B-DNA . RNA adopts this double helical form, and RNA-DNA duplexes are mostly A-form, but B-form RNA-DNA duplexes have been observed.
39.
It is shorter and wider than B-DNA . RNA adopts this double helical form, and RNA-DNA duplexes are mostly A-form, but B-form RNA-DNA duplexes have been observed.
40.
These overhangs are then bound to form a nucleoprotein filament, which can then locate DNA sequences similar to one of the 3 overhangs, initiating a single-stranded strand invasion into the DNA duplex containing these sequences.
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