Using atropine as an antidote to nerve agents requires an initial dose ranging from 2 milligrams to 4 milligrams, then 2 milligrams repeated every five or 10 minutes until the symptoms disappear, a council diplomat said.
32.
A recent study reports on the preclinical validation of 111In-labeled anti-DR5 humanised antibody CS-1008 as a diagnostic tool to study the DR5 occupancy in cancer patients, and establish dose ranges for receptor saturation kinetics in vivo.
33.
In addition to this, the device has a very wide target dose range of between 2 and 5, 000 rads ( 20 mGy to 50 Gy ) which makes the technology widely applicable to nuclear decommissioning applications.
34.
It has been well tolerated in human trials even at high dose ranges with no evidence for cognitive dysfunction, and has completed Phase II clinical trials for the treatment of osteoarthritis, but was found to be ineffective.
35.
Due to the high concentrations achieved, progesterone by intramuscular injection at the usual clinical dose range is able to suppress gonadotropin secretion from the pituitary gland, demonstrating antigonadotropic efficacy ( and therefore suppression of gonadal sex steroid production ).
36.
The oral administration of tomatine in doses of 15-30 mg / kg or the intramuscular admistration in the dose range of 1-10 mg / kg induces a dose-dependent inhibition of induced edema similar anti-inflammatory effects are noted when tomatine is administered subcutaneously.
37.
A 1999 clinical dose ranging study in " eight male volunteers with'tannable'skin types III-IV " given [ Nle 4, D-Phe 7 ] ?-MSH ( Melanotan-I ) determined that an optimal dose for ten daily subcutaneous injections is 0.16 mg / kg per day.
38.
"Initial Treatment for Acute Bacterial Skin Infections ( ABSSSI ) Caused by Staphylococcus aureus " " Randomized, Dose Ranging, Active Controlled Efficacy and Safety Evaluation of PMX-30063 As Initial Treatment for Acute Bacterial Skin and Skin Structure Infections ( ABSSSI ) Caused by Staphylococcus aureus"
39.
The pharmacokinetics of continuous subcutaneous treprostinil are linear over the dose range of 1.25 to 125 ng / kg / min ( corresponding to plasma concentrations of about 15 pg / mL to 18, 250 pg / m ) and can be described by a two-compartment model.
40.
PMA overdose can be a serious medical emergency that may occur at only slightly above the usual recreational dose range, especially if PMA is mixed with other stimulant drugs such as cocaine or MDMA . Characteristic symptoms are pronounced hyperthermia, tachycardia, and hypertension, along with agitation, confusion, and convulsions.
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