31. Drugs and poisons are often enzyme inhibitors . 32. Such information can then be used to guide organic synthesis for high-affinity protein ligands and enzyme inhibitors . 33. Angiotensin-converting-enzyme inhibitors , or ACE inhibitors, are a class of widely-prescribed medications used in hypertension and heart failure. 34. However, not all drugs are enzyme inhibitors . 35. MLN4924, a NEDD8-activating enzyme inhibitor functioning according to similar mechanisms, is currently undergoing phase I clinical trials. 36. It is an inhibitor of the enzyme thermolysin, a membrane metallo-endopeptidase inhibitor, and an endothelin converting enzyme inhibitor . 37. He was also instrumental in the writing and successful nomination of the featured articles Enzyme and Enzyme inhibitor . 38. In cell biology aprotinin is used as an enzyme inhibitor to prevent protein homogenization of cells and tissues. 39. These enzyme inhibitors interfere with digestion. 40. The activity of trypsin is not affected by the enzyme inhibitor tosyl phenylalanyl chloromethyl ketone, TPCK, which deactivates chymotrypsin.