Epithelial layers contain no blood vessels, so they must receive nourishment via diffusion of substances from the underlying connective tissue, through the basement membrane . Cell junctions are well-employed in epithelial tissues.
32.
The chief doctor initiated a postmortem examination, in which superficial and bleeding damages of the epithelial layer were detected spread all over the back, especially on the protruding parts of the back, the back of the head and the upper arm.
33.
For instance, when an epithelial layer is complete and the adherens junctions indicate that the cell is surrounded, ?-catenin may play a role in telling the cell to stop proliferating, as there is no room for more cells in the area.
34.
Mutations in three of the proteins in the complement cascade have been identified in patients with atypical HUS . Several chemotherapeutic drugs have also been shown to cause damage to the epithelial layer by reducing the ability for the cells to produce prostacyclin, ultimately resulting in chemotherapy-associated HUS, or C-HUS.
35.
The first study of perlecan expression during embryonal development found that the protein was first expressed during development of the cardiovascular system, and later correlates with maturation of the majority of tissues in the body, i . e . separation of epithelial layers from endothelia and stroma by basement membranes.
36.
First of all, by binding to cadherin receptor intracellular cytoplasmic tail domains, it can act as an integral component of a protein complex in adherens junctions that helps cells maintain epithelial layers . ?-catenin acts by anchoring the actin cytoskeleton to the junctions, and may possibly aid in contact inhibition signaling within the cell.
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