Estriol is cleared from the circulation rapidly in pregnant women so circulating levels are very low, but concentrations of estriol in the urine are relatively high.
32.
Estriol is cleared from the circulation rapidly in pregnant women so circulating levels are very low, but concentrations of estriol in the urine are relatively high.
33.
Estetrol is synthesized in the fetal liver from estradiol ( E2 ) and estriol ( E3 ) by the two enzymes 15?-and 16?-hydroxylase.
34.
Estrone is the least abundant of the three hormones; estradiol is present almost always in the reproductive female body, and estriol is abundant primarily during pregnancy.
35.
Ethinyl estriol has not been marketed, but nilestriol, which is the 3-cyclopentyl ether of ethinyl estriol and a prodrug of it, has been.
36.
Ethinyl estriol has not been marketed, but nilestriol, which is the 3-cyclopentyl ether of ethinyl estriol and a prodrug of it, has been.
37.
GPER binds estradiol though not other endogenous estrogens, such as estrone or estriol, nor for other endogenous steroids, including progesterone, testosterone, and cortisol.
38.
The positional isomer of estriol 16?-glucuronide, estriol 3-glucuronide, also occurs as an endogenous metabolite of estriol, although to a much lower extent in comparison.
39.
The positional isomer of estriol 16?-glucuronide, estriol 3-glucuronide, also occurs as an endogenous metabolite of estriol, although to a much lower extent in comparison.
40.
The positional isomer of estriol 16?-glucuronide, estriol 3-glucuronide, also occurs as an endogenous metabolite of estriol, although to a much lower extent in comparison.
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