31. Of course, fibroblasts are not supposed to turn into bone or cartilage. 32. His work with fibroblasts began in the late 1980s. 33. They began with fibroblasts , or fetal skin and connective-tissue cells. 34. Fibroblasts are morphologically heterogeneous with diverse appearances depending on their location and activity.35. Like other cells of connective tissue, fibroblasts are derived from primitive mesenchyme. 36. Pre-adipocytes are undifferentiated fibroblasts that can be stimulated to form adipocytes. 37. Fibroblasts also secrete growth factors that attract epithelial cells to the wound site.38. Second, there is cellular differentiation of mesenchymal cells into osteoblasts or fibroblasts . 39. The surrounding stromal cells ( fibroblasts ) also proliferate. 40. Gene mutations in PHEX prevent it from correctly regulating fibroblast growth factor 23.
