31. The advanced lesion is no longer localized to the area around the gingival sulcus but spreads gum tissue papilla. 32. Wound " healing following gingival surgery was enhanced due to the antimicrobial effects of topically administered hydrogen peroxide ". 33. The gingival tissue of the gums also tends to suffer permanent effects once the disease reaches a certain point. 34. The often severe gingival pain that characterizes ANUG distinguishes it from the more common chronic periodontitis which is rarely painful. 35. Additionally, brushing twice daily with a toothpaste containing stannous fluoride may reduce gingivitis, gingival bleeding and dental plaque. 36. The buccal cusp ridges exhibit slight concavities that extend over the buccal surfaces as developmental grooves into the gingival embrasure. 37. In a gingival pocket, no destruction of the connective tissue fibers ( gingival fibers ) or alveolar bone occurs. 38. In a gingival pocket, no destruction of the connective tissue fibers ( gingival fibers ) or alveolar bone occurs. 39. As the gingival tissue swells, it no longer provides an effective seal between the tooth and the outside environment. 40. Reversing and preventing gingival enlargement caused by drugs is as easy as ceasing drug therapy or substituting to another drug.