31. Big Brain apparently suffers from an extreme case of hydrocephalus and goitres , explaining his large distended head and bloated throat. 32. He did major research in endomyocardial fibrosis, endemic goitre , sickle-cell disease and other areas of national need. 33. The disease was later named after Irish doctor Robert James Graves, who described a case of goitre with exophthalmos in 1835. 34. Enlarged goitres may extend beyond the normal position of the thyroid gland to below the sternum, around the airway or esophagus. 35. Roberto Goitre founded two choirs, the Piccoli Cantori in Turin in 1972 and the Coro Polifonico Farnesiano in Piacenza in 1976. 36. Diffuse goitre may be seen with other causes of hyperthyroidism, although Graves'disease is the most common cause of diffuse goitre. 37. Diffuse goitre may be seen with other causes of hyperthyroidism, although Graves'disease is the most common cause of diffuse goitre . 38. Craddock travels to Scotland to meet Belle; she mentions that Letitia had a beloved sister, Charlotte, who developed a goitre . 39. Purves played a leading role in the abolition of thyroid enlargement ( goitre ) which once disfigured nearly 20 % of the population. 40. He also carried out human experiments aimed at identifying the cause of goitre , and included himself as one of the experimental subjects.
