31. Lick granulomas are especially seen in active dogs left alone for long periods of time. 32. The most common benign coin lesion is a granuloma ( inflammatory dog heartworm infestation ). 33. This granuloma mimics a squamous cell tumour. 34. Granulomas are seen in a wide variety of diseases, both infectious and non-infectious.35. An August 2015 review notes that dapsone is reported to be effective against generalized granuloma annulare. 36. Ocular granulomas that form around a larva typically are peripheral in the retina or optic disc. 37. Granulomas may form around eggs and can cause seizures, neurologic deficits, or cardiac insufficiency.38. However, in the lung, extensive caseous necrosis with confluent cheesy tan granulomas is typical. 39. A biopsy of the later lesions reveals granuloma formation with plant material embedded in the dermis. 40. Lick granulomas are especially seen in large active dogs left alone for long periods of time.