31. The small 8-kilodalton protein ubiquitin, which marks proteins for degradation, also has features of a heat shock protein . 32. In this process heat shock protein is dissociated, and the activated receptor-ligand complex is translocated into the nucleus. 33. It has similarities to heat shock proteins and clathrin-associated proteins, and may be involved in vesicle structure or trafficking. 34. A kinase of the nitric oxide cell signalling pathway, protein kinase G, phosphorylates a small heat shock protein , hsp20. 35. However, when cells are heated, the fraction of heat shock proteins increases to 4 6 % of cellular proteins. 36. SMYD3 has been shown to interact with Heat shock protein 90kDa alpha ( cytosolic ), member A1 and POLR2A. 37. Another way in which hyperthermophiles ensure their proteins'proper function is through the use of heat shock proteins ( HSPs ). 38. EPRS has been shown to interact with POU2F1, Heat shock protein 90kDa alpha ( cytosolic ), member A1 and IARS. 39. This topic is currently classified as a stub with a basic introduction to heat shock proteins with just one reference. 40. The protein encoded by this gene was originally suggested to be a member of the heat shock protein 70 family.