31. Arenobufagin is also toxic for hepatocellular carcinoma cells, which is a positive result for the body. 32. In 2010, researchers developed an applicable targeting therapy for hepatocellular carcinoma ( HCC ) in humans. 33. It has been found that miR-130 is upregulated in a type of cancer called hepatocellular carcinoma . 34. This type of infection dramatically increases the incidence of hepatocellular carcinoma ( HCC; liver cancer ). 35. Mutations in this gene have been associated with hepatocellular carcinoma , hepatoblastomas, ovarian endometriod adenocarcinomas, and medulloblastomas. 36. Integrative analysis in hepatocellular carcinoma implicates Stathmin 1 ( STMN1 ) as a downstream target of miR-223. 37. Once cirrhosis is established, the rate of developing hepatocellular carcinoma is ~ 1 4 % per year. 38. While infection is commonly asymptomatic both cirrhosis with liver failure and hepatocellular carcinoma may occur in childhood. 39. Expression of this RNA gene has been found to dramatically increase in hepatocellular carcinoma ( HCC ) cells. 40. Increased gene expression ( as observed by an increase in mRNA levels ) is associated with hepatocellular carcinomas .
