31. The loss of the functional copy is called " loss of heterozygosity " ( LOH ). 32. When mutation results in loss of heterozygosity at tumor suppressor gene sites, these genes may become inactive. 33. Allendorf also has many papers published on the effects of genetics and heterozygosity on the development of organisms. 34. The effective population size is most commonly measured with respect to the heterozygosity is equal to 4N \ mu. 35. As a result, compound heterozygosity for hemochromatosis may be more common than diagnosis based on pathology would suggest. 36. Another research area is focused on loss of heterozygosity , a side effect of DNA-repair and recombination. 37. Under the mechanism of natural selection, therefore, homozygosity would be favoured over heterozygosity , eventually leading to speciation. 38. Heterozygosity for this mutant allele also has shown to improve one's virological response to anti-retroviral treatment.39. Many of the mutations cause or probably cause hemochromatosis phenotypes, often in compound heterozygosity with " HFE" 40. Types of mutations include frameshift, nonsense, missense, splicing alteration and deletion mutations, and loss of heterozygosity .
