However, the patient also had pulmonary histiocytosis X . While this may have been a coincidence, such patients have many abnormalities of the immune system including imbalance of the immunoregulatory cell system and a decreased production of natural antibodies.
32.
"' Langerhans cell histiocytosis ( LCH ) "': LCH is an aggressive disorder due to proliferation of Langerhans cell hystiocytes, and the dentate nucleus is believed to be involved in up to 40 percent of patients.
33.
Jeff Toughill, the president of the Histiocytosis Association of America in Pittman, N . J ., said the rare nature of the disease, as well as its many different manifestations, can make patients and their families feel alone.
34.
Types of LCH have also been known as " Eosinophilic Granuloma ", " Hand-Schuller-Christian Disease ", " Letterer-Siwe Disease ", and " Histiocytosis X " . ( See Langerhans cell histiocytosis for details ).
35.
Types of LCH have also been known as " Eosinophilic Granuloma ", " Hand-Schuller-Christian Disease ", " Letterer-Siwe Disease ", and " Histiocytosis X " . ( See Langerhans cell histiocytosis for details ).
36.
In medicine, "'histiocytosis "'refers to an excessive number of histiocytes, ( " tissue macrophages " ), and is typically used to refer to a group of rare diseases which share this as a characteristic.
37.
The disease has gone by several names, including Hand Sch�ller Christian disease, "'Abt-Letterer-Siwe disease "', and "'histiocytosis X "', until it was renamed in 1985 by the Histiocyte Society.
38.
A diagnosis of CRMO is often made after a bone biopsy and MRI have ruled out other diseases that cause painful bone lesions / tumors such as bacterial osteomyelitis, ewing sarcoma, leukemia, lymphoma, rhabdomyosarcoma, neuroblastoma metastasis, eosinophilic granuloma, or Langerhans cell histiocytosis.
39.
"' Langerhans cell histiocytosis "'( "'LCH "') is a rare disease involving clonal proliferation of Langerhans cells, abnormal histiocytoses, which are characterized by an abnormal proliferation of histiocytes ( an archaic term for activated dendritic cells and macrophages ).
40.
If central DI is suspected, testing of other hormones of the pituitary, as well as magnetic resonance imaging, particularly a pituitary MRI, is necessary to discover if a disease process ( such as a prolactinoma, or histiocytosis, syphilis, tuberculosis or other tumor or granuloma ) is affecting pituitary function.
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